Development and applications of single-cycle infectious Influenza A Virus (sciIAV)
Identifieur interne : 000578 ( Main/Exploration ); précédent : 000577; suivant : 000579Development and applications of single-cycle infectious Influenza A Virus (sciIAV)
Auteurs : Aitor Nogales ; Steven F. Baker ; William Domm ; Luis Martínez-SobridoSource :
- Virus research [ 0168-1702 ] ; 2015.
Abstract
The diverse host range, high transmissibility, and rapid evolution of influenza A viruses justify the importance of containing pathogenic viruses studied in the laboratory. Other than physically or mechanically changing influenza A virus containment procedures, modifying the virus to only replicate for a single round of infection similarly ensures safety and consequently decreases the level of biosafety containment required to study highly pathogenic members in the virus family. This biological containment is more ideal because it is less apt to computer, machine, or human error. With many necessary proteins that can be deleted, generation of single-cycle infectious influenza A viruses (sciIAV) can be achieved using a variety of approaches. Here, we review the recent burst in sciIAV generation and summarize the applications and findings on this important human pathogen using biocontained viral mimics.
Url:
DOI: 10.1016/j.virusres.2015.07.013
PubMed: 26220478
PubMed Central: 4728073
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 000869
- to stream Pmc, to step Curation: 000869
- to stream Pmc, to step Checkpoint: 000411
- to stream Ncbi, to step Merge: 000C00
- to stream Ncbi, to step Curation: 000C00
- to stream Ncbi, to step Checkpoint: 000C00
- to stream Main, to step Merge: 000579
- to stream Main, to step Curation: 000578
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Development and applications of single-cycle infectious Influenza A Virus (sciIAV)</title>
<author><name sortKey="Nogales, Aitor" sort="Nogales, Aitor" uniqKey="Nogales A" first="Aitor" last="Nogales">Aitor Nogales</name>
</author>
<author><name sortKey="Baker, Steven F" sort="Baker, Steven F" uniqKey="Baker S" first="Steven F." last="Baker">Steven F. Baker</name>
</author>
<author><name sortKey="Domm, William" sort="Domm, William" uniqKey="Domm W" first="William" last="Domm">William Domm</name>
</author>
<author><name sortKey="Martinez Sobrido, Luis" sort="Martinez Sobrido, Luis" uniqKey="Martinez Sobrido L" first="Luis" last="Martínez-Sobrido">Luis Martínez-Sobrido</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">26220478</idno>
<idno type="pmc">4728073</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728073</idno>
<idno type="RBID">PMC:4728073</idno>
<idno type="doi">10.1016/j.virusres.2015.07.013</idno>
<date when="2015">2015</date>
<idno type="wicri:Area/Pmc/Corpus">000869</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000869</idno>
<idno type="wicri:Area/Pmc/Curation">000869</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000869</idno>
<idno type="wicri:Area/Pmc/Checkpoint">000411</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000411</idno>
<idno type="wicri:Area/Ncbi/Merge">000C00</idno>
<idno type="wicri:Area/Ncbi/Curation">000C00</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">000C00</idno>
<idno type="wicri:doubleKey">0168-1702:2015:Nogales A:development:and:applications</idno>
<idno type="wicri:Area/Main/Merge">000579</idno>
<idno type="wicri:Area/Main/Curation">000578</idno>
<idno type="wicri:Area/Main/Exploration">000578</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Development and applications of single-cycle infectious Influenza A Virus (sciIAV)</title>
<author><name sortKey="Nogales, Aitor" sort="Nogales, Aitor" uniqKey="Nogales A" first="Aitor" last="Nogales">Aitor Nogales</name>
</author>
<author><name sortKey="Baker, Steven F" sort="Baker, Steven F" uniqKey="Baker S" first="Steven F." last="Baker">Steven F. Baker</name>
</author>
<author><name sortKey="Domm, William" sort="Domm, William" uniqKey="Domm W" first="William" last="Domm">William Domm</name>
</author>
<author><name sortKey="Martinez Sobrido, Luis" sort="Martinez Sobrido, Luis" uniqKey="Martinez Sobrido L" first="Luis" last="Martínez-Sobrido">Luis Martínez-Sobrido</name>
</author>
</analytic>
<series><title level="j">Virus research</title>
<idno type="ISSN">0168-1702</idno>
<idno type="eISSN">1872-7492</idno>
<imprint><date when="2015">2015</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p id="P2">The diverse host range, high transmissibility, and rapid evolution of influenza A viruses justify the importance of containing pathogenic viruses studied in the laboratory. Other than physically or mechanically changing influenza A virus containment procedures, modifying the virus to only replicate for a single round of infection similarly ensures safety and consequently decreases the level of biosafety containment required to study highly pathogenic members in the virus family. This biological containment is more ideal because it is less apt to computer, machine, or human error. With many necessary proteins that can be deleted, generation of single-cycle infectious influenza A viruses (sciIAV) can be achieved using a variety of approaches. Here, we review the recent burst in sciIAV generation and summarize the applications and findings on this important human pathogen using biocontained viral mimics.</p>
</div>
</front>
</TEI>
<affiliations><list></list>
<tree><noCountry><name sortKey="Baker, Steven F" sort="Baker, Steven F" uniqKey="Baker S" first="Steven F." last="Baker">Steven F. Baker</name>
<name sortKey="Domm, William" sort="Domm, William" uniqKey="Domm W" first="William" last="Domm">William Domm</name>
<name sortKey="Martinez Sobrido, Luis" sort="Martinez Sobrido, Luis" uniqKey="Martinez Sobrido L" first="Luis" last="Martínez-Sobrido">Luis Martínez-Sobrido</name>
<name sortKey="Nogales, Aitor" sort="Nogales, Aitor" uniqKey="Nogales A" first="Aitor" last="Nogales">Aitor Nogales</name>
</noCountry>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/H2N2V1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000578 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000578 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Sante |area= H2N2V1 |flux= Main |étape= Exploration |type= RBID |clé= PMC:4728073 |texte= Development and applications of single-cycle infectious Influenza A Virus (sciIAV) }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:26220478" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \ | NlmPubMed2Wicri -a H2N2V1
This area was generated with Dilib version V0.6.33. |